Overview and Clinical Significance
Lipase is an enzyme responsible for fat digestion, breaking down triglycerides into glycerol and free fatty acids. It is primarily produced by the pancreas, with smaller amounts secreted by the stomach and salivary glands.
Clinical Significance
- Pancreatic Function & Disorders: Elevated lipase levels indicate pancreatitis, pancreatic duct obstruction, or pancreatic tumors.
- Digestive Health & Malabsorption: Lipase plays a role in fat absorption, with deficiencies linked to exocrine pancreatic insufficiency (EPI).
- Metabolic & Cardiovascular Effects: Lipase activity influences lipid metabolism, affecting cholesterol balance and cardiovascular health.
- Diagnostic & Therapeutic Applications: Lipase testing is used to diagnose pancreatic disorders, monitor digestive health, and assess metabolic conditions.
Lipase is a key enzyme in fat metabolism, pancreatic health, and digestive efficiency.
