Overview and Clinical Significance
Cancer Associated Serum Antigen (CASA) is a tumor marker primarily studied in breast cancer, though its clinical utility remains less established compared to other markers like CA 15-3 and CA 549. CASA is a polymorphic epithelial mucin, detected using monoclonal antibodies, and has been explored for its predictive value in cancer progression.
Clinical Significance
- Breast Cancer Detection & Monitoring: CASA levels have been examined in breast carcinoma patients, but studies suggest it may be less valuable than other tumor markers.
- Comparison with Other Tumor Markers: Research indicates CASA is not as sensitive or specific as CA 15-3, CA 549, or CEA, limiting its diagnostic application.
- Potential Role in Cancer Prognosis: While CASA has been studied for tumor burden assessment, its clinical relevance remains under investigation.
CASA is a tumor marker with limited clinical utility, primarily explored in breast cancer research.
