Overview and Clinical Significance
Serum complement refers to a group of proteins in the immune system that play a crucial role in pathogen defense, inflammation regulation, and immune surveillance. These proteins work together in a cascade mechanism, enhancing the body's ability to fight infections.
Clinical Significance
- Immune Defense & Infection Control: Complement proteins help destroy bacteria, viruses, and damaged cells.
- Autoimmune & Inflammatory Disorders: Abnormal complement levels are linked to autoimmune diseases like lupus and rheumatoid arthritis.
- Complement Deficiencies & Genetic Disorders: Deficiencies in complement proteins can lead to increased susceptibility to infections and immune dysfunction.
- Diagnostic & Therapeutic Applications: Serum complement testing helps assess immune system activity, inflammation, and disease progression.
Serum complement is a key regulator of immune health, influencing infection resistance, inflammation control, and autoimmune disease management.
