Proteinuria
Overview & Clinical Significance
Proteinuria refers to the presence of excess protein in the urine, often signaling kidney dysfunction. Healthy kidneys filter waste while retaining essential proteins in the bloodstream, but when protein leaks into the urine, it may indicate damage to the kidney’s filtering units (glomeruli) or other underlying conditions.
Persistent proteinuria can be a marker of chronic kidney disease (CKD), diabetes-related nephropathy, autoimmune disorders like lupus nephritis, or cardiovascular conditions such as hypertension and preeclampsia.
Temporary increases may occur due to infections, inflammation, exercise, or stress, but sustained elevations warrant further investigation. Detecting proteinuria early helps prevent progressive kidney damage, guiding interventions that protect renal function and overall health.
